Disturbances of Pain Perception in Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, tenderness, disturbed sleep and pronounced fatigue (Boissevain & McCain, 1991a,b). A number of associated symptoms, such as morning stiffness, headache, subjective swelling, paresthesiae, irritable bowel syndrome, irritable bladder and psychological distress are commonly seen in FM patients. The pain present in FM is migrating, i.e., the localization of maximal pain intensity differs from day to day. Using the McGill pain questionnaire FM patients described their pain as being anatomically more extensive and stronger regarding the sensory and affective pain dimensions than did patients with rheumatoid arthritis (RA) (Uveges, Parker, Smarr, McGowan, Lyon, Irvin, Meyer, Buckelew, Morgan, Delmonico, Hewett, & Kay, 1990). However, in other studies, the sensory, affective, and evaluative scores were essentially equal for the FM and RA patients (Leavitt, Katz, Golden, Glickman, & Layfer, 1986; Nolli, Ghirelli, & Ferraccioli, 1988).
KeywordsPain Threshold Temporal Summation Fibromyalgia Syndrome Pressure Pain Threshold Quantitative Sensory Testing
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- Burckhardt, C.S., Clark, S.R., Campbell, S.M., O’Reilly, C.A., & Bennett, R.M. (1995). Events and co-morbidities associated with the onset of fibromyalgia. Journal of Musculoskektal Pain, 3, 71.Google Scholar
- Henriksson, K-G, & Mense, S. (1994). Pain and nociception in fibromyalgia: clinical and neurobiological considerations on aetiology and pathogenesis. Pain Reviews, 1, 245–260.Google Scholar
- Jacobsen, S., & Danneskiold-Samsoe, B. (1989). Inter-relations between clinical parameters and muscle function in patients with primary fibromyalgia. Clinical-Experimental Rheumatology, 7, 493–498.Google Scholar
- Kwaitek, R., Barnden, L., Tedman, R., Jarrett, R., Chew, J., Rowe, C., & Pile, K. (2000). Regional cerebral blood flow in fibromyalgia. Single-photon-emission computed tomography evidence of reduction in the pontine tegmentum and thalami. Arthritis and Rheumatism, 43, 2823–2833.CrossRefGoogle Scholar
- Moldofsky, H., (1990). The contribution of sleep-wake physiology to fibromyalgia. In J.R. Fricton & E. Awad (Eds.), Advances in pain research and therapy. (pp. 227–240). New York: Raven Press.Google Scholar
- Nolli, M., Ghirelli, L., & Ferraccioli, G. (1988). Pain language in fibromyalgia, rheumatoid arthritis and osteoarthritis. Clinical Experimental Rheumatology, 6, 27–33.Google Scholar
- Rollman, G., & Lautenbacher, S. (1993). Hypervigilance effects in fibromyalgia: pain experience and pain perception. In H. Vaeroy & H. Merskey (Eds.), Progress in fibromyalgia and myofascial pain. (pp. 149–159). Amsterdam: Elsevier Science Publishers.Google Scholar
- Smythe, H.A. (1979). ‘Fibrositis’ as a disorder of pain modulation. Clinical Rheumatologkal Diseases, 5, 823–832.Google Scholar
- Stefano, R., Selvi, E., Villanova, M., Frati, E., Manganelli, S., Franceschini, E., Baisi, G., & Marcolongo, R. (2000).Image analysis quantification of substance P immunorcactivity in the trapezius muscle of patients with fibromyalgia and myofascial pain syndrome. Journal of Rheumatology, 27, 2906–2910.PubMedGoogle Scholar
- Uveges,J.M., Parker, J.C., Smarr, K.C., McGowan, J.F., Lyon, M.G., Irvin, W.S., Meyer, A.A., Buckelew, S.P., Morgan, R.K., Delmonico, R.L., Hcwett, J.E., & Kay, D.R. (1990). Psychological symptoms in primary fibromyalgia syndrome: relationship to pain, life stress, and sleep disturbance. Arthritis & Rheumatism, 33, 1279–1283.CrossRefGoogle Scholar
- Van Denderen, J.C.V., Boersma, J.W., Zeinstra, P., Hollander, A.P., & Neerbos, B.R.V (1992). Physiological effects of exhaustive physical exercise in primary fibromyalgia syndrome (PFS): Is PFS a disorder of neuroendocrine reactivity? Scandiavian Journal of Rheumatology, 21, 35–37.CrossRefGoogle Scholar
- Wolfe, F., Smythe, H.A., Yunus, M.B., Bennett, R.B., Bombardier, C., Goldenberg, D.L., Tugwell, P., Campbell, S.M., Abeles, M., Clark, P., Farn, A.G., Farber, S.J., Fiechtner, J.J., Franklin, C.M., Gatter, R.A., Hamaty, D., Lessard, J., Lichtbroun, A.S., Masi, A.T., McCain, G.A., Reynolds, W.J., Romano, T.J., Russell, I.J., & Sheon, R.P. (1990). The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Arthritis & Rheumatism, 33, 160–172.Google Scholar