Disturbances of Pain Perception in Disorders of the Peripheral Nervous System

  • Karsten Schepelmann
Part of the Plenum Series in Rehabilitation and Health book series (SSRH)

Abstract

Diabetic neuropathy is one of the most common forms of polyneuropathy. The prevalence among diabetics has been reported as 30% (Tesfaye et al., 1996), and it occurs as a complication of type I (insulin dependent diabetes mellitus, IDDM) as well as type II (non-insulin dependent diabetes mellitus, NIDDM). Its incidence increases with age and duration of diabetes. Diabetic neuropathy affects small and large nerve fibers with varying proportions. In some cases small nerve fiber dysfunction is predominant, leading to autonomic symptoms and disturbance of wound healing. There are several different clinical manifestations with subtypes in terms of the pattern of neurological disturbances, which are presented in the following paragraphs. However, mixed forms of these manifestations occur (Sommer, Donaghy & Wiethölter, 1996).

Keywords

Neuropathy Flare Histamine Catecholamine Rosen 

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© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Karsten Schepelmann
    • 1
  1. 1.Department of NeurologyUniversity of MarburgMarburgGermany

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