Diseases of the Biliary Tree in Infancy and Childhood

  • Pierre Russo
  • Elizabeth B. Rand
  • Barbara Anne Haber


The division of this chapter into diseases of the extrahepatic and intrahepatic biliary tree is arbitrary, as many of the major entities discussed, such as biliary atresia and sclerosing cholangitis, have both intra- and extrahepatic manifestations. Diseases of the biliary tree represent an important group of disorders, many of which manifest in the neonate and infant. At The Children’s Hospital of Philadelphia, liver biopsies performed for the evaluation of cholestasis in the infant or young child constitute approximately 33% of all native liver biopsies accessioned by the pathology department, mirroring the experience of other pediatric referral institutions. The pathologist’s role in the evaluation of these biopsy samples is often pivotal as to the timing and need for surgical intervention and orientation of the clinical evaluation. This chapter will begin with a general overview and discussion of jaundice in the neonate and in the older child and will be followed by a discussion of individual entities.


Bile Duct Primary Sclerosing Cholangitis Biliary Atresia Biliary Tree Sclerosing Cholangitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Pierre Russo
  • Elizabeth B. Rand
  • Barbara Anne Haber

There are no affiliations available

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