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Lewis and the Somatic Effects of Ionizing Radiation

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Genes, Development and Cancer
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Abstract

In 1927, H. J. Muller proved that ionizing radiation causes genetic mutations (Muller, 1927). Muller found that, in X-irradiated Drosophila, the mutation rate was almost 200-fold that seen in control, unirradiated flies. The spectrum of mutations obtained ranged from lethals to visibles, recessives to dominants, ‘invisible’ lesions to chromosomal rearrangements. Similar effects were seen when either sperm or oocytes were irradiated.

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© 2004 Springer Science+Business Media New York

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Lipshitz, H.D. (2004). Lewis and the Somatic Effects of Ionizing Radiation. In: Lipshitz, H.D. (eds) Genes, Development and Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8981-9_25

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  • DOI: https://doi.org/10.1007/978-1-4419-8981-9_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4746-0

  • Online ISBN: 978-1-4419-8981-9

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