Abstract
The photodynamic diagnosis is a new technique for early detection of flat urothelial lesions or cancer of the bladder. After intravesical application of 5-Aminolevulinic acid (5-ALA), a fluorescence cystoscopy for photodetection of tiny tumors in the bladder can be made. We investigated whether it is easier to recognize neoplasias or dysplasias of the bladder by fluorescence cystoscopy than it is to recognize them by conventional white light cystoscopy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Althausen A, Prout G, Daly J: Non-invasive papillary carcinoma of the bladder associated with carcinoma in situ. J Urol, 116:575, 1976.
Filbeck T, Roessler W, Knuechel R, Straub M, Kiel HJ, Wieland WF: 5-aminolevulinic acid-induced fluorescence endoscopy applied at secondary transurethral resection after conventional resection of primary superficial bladder tumors. Urology, (53) 1:77, 1999.
Jichlinski P, Wagnieres G, Forrer M, Mizeret J, Guillou L, Oswald M, et al: Clinical assessment of fluorescence cystoscopy during transurethral bladder resection in superficial bladder cancer. Urological Research, 25 Suppl. l:3, 1997.
Kriegmair M, Baumgärtner R, Knüchel R, Stepp H, Hofstadter F, Hofstetter A: Detection of early bladder cancer by 5-Aminolevulinic acid induced porphyrin fluorescence. J Urol, 155:105, 1996.
Hofstaedter F, Delgado R, Jakse G, Judmaier W: Urothelial dysplasia and carcinoma in situ of the bladder. Cancer, 57:356, 1986
Murphy W, Soloway M: Urothelial dysplasia. J Urol, 127:849, 1982.
Sanchez-Fernandez de Sevilla M, Morell-Quadreny L, Gil-Salom M, Perez-Bacete M, Llombart-Bosch A: Morphometric and immunohistochemical characterization of bladder carcinoma in situ and in preneoplastic lesions. Eur Urol, 21 Suppl 1:5, 1992.
Smith G, Elton RA, Beylon LL, Newsam JE, Chrisholm GD, Hargreave TB: Prognostic significance of biopsy results of normal looking mucosa in cases of superficial bladder cancer. Br J Urol, 55:665, 1983.
Zumbraegel A, Bichler K-H: Die photodynamische Diagnostik (PDD) zur Erkennung von Blasentumoren. In: Bichler K-H, Wilbert D, Wechsel HW, Strohmaier WL, editors. Diagnostik und Therapie des Harnblasenkarzinoms. Germany: Einhorn-Presse-Verlag, 1998.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer Science+Business Media New York
About this chapter
Cite this chapter
Zumbraegel, A., Bichler, KH., Krause, F.S., Feil, G., Nelde, H.J. (2003). The Photodynamic Diagnosis (PDD) for Early Detection of Carcinoma and Dysplasia of the Bladder. In: Atala, A., Slade, D. (eds) Bladder Disease, Part A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8889-8_5
Download citation
DOI: https://doi.org/10.1007/978-1-4419-8889-8_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4707-1
Online ISBN: 978-1-4419-8889-8
eBook Packages: Springer Book Archive