Protocol for MRI Monitoring of Orthotopic Glioma Growth in the Rat Brain

  • Roland H. Goldbrunner
  • Martin Bendszus
  • Jörg-Christian Tonn
Part of the Cancer Treatment and Research book series (CTAR, volume 117)

Abstract

The following protocol has been developed for monitoring tumor volumes and tumor morphology of C6 gliomas, which have been implanted as spheroids subcortically into the brains of male Sprague-Dawley rats weighting 300–350 g (Fig. 1).

Keywords

Xylazin Volumetry 

Reference

  1. 1.
    Goldbrunner RH, Bendszus M, Sasaki M, et al: Vascular endothelial growth factor-driven glioma growth and vascularization in an orthotopic rat model monitored by magnetic resonance imaging. Neurosurgery 47:921-929, 2000.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2004

Authors and Affiliations

  • Roland H. Goldbrunner
    • 1
  • Martin Bendszus
    • 1
    • 2
  • Jörg-Christian Tonn
    • 1
  1. 1.Department of NeurosurgeryUniversity of MunichMunich
  2. 2.Division of NeuroradiologyUniversity of WürzburgWürzburgGermany

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