Acoustical Imaging pp 175-182

Part of the Acoustical Imaging book series (ACIM, volume 26)

Computerized Ultrasound Risk Evaluation (CURE) System: Development of Combined Transmission and Reflection Ultrasound with New Reconstruction Algorithms for Breast Imaging

  • Peter J. Littrup
  • Neb Duric
  • Stephen Azevedo
  • David Chambers
  • James V. Candy
  • Stephen Johnson
  • Gregory Auner
  • John Rather
  • Earle T. Holsapple

Abstract

Our Computerized Ultrasound Risk Evaluation (CURE) system has been developed to the engineering prototype stage and generated unique data sets of both transmission and reflection ultrasound (US). This paper will help define the clinical underpinnings of the developmental process and interpret the imaging results from a similar perspective. The CURE project was designed to incorporate numerous diagnostic parameters to improve upon two major areas of early breast cancer detection. CURE may provide improved tissue characterization of breast masses and reliable detection of abnormal microcalcifications found in some breast cancers and ductal carcinoma in situ (DCIS). Current breast US is limited to mass evaluation, whereas mammography also detects and guides biopsy of malignant calcifications. Screening with CURE remains a distant goal, but improved follow-up of mammographic abnormalities may represent a feasible breakthrough.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Peter J. Littrup
    • 1
    • 2
  • Neb Duric
    • 3
  • Stephen Azevedo
    • 4
  • David Chambers
    • 4
  • James V. Candy
    • 4
  • Stephen Johnson
    • 5
  • Gregory Auner
    • 6
  • John Rather
    • 7
  • Earle T. Holsapple
    • 7
  1. 1.Departments of RadiologyWayne State UniversityDetroit
  2. 2.Karmanos Cancer InstituteDetroit
  3. 3.Department of Physics and AstronomyAlbuquerque
  4. 4.Lawrence Livermore National LaboratoryLivermore
  5. 5.TechniScan IncSalt Lake City
  6. 6.Dept. of Electrical and Computer EngineeringWayne State UniversityDetroit
  7. 7.Karmanos Cancer InstituteDetroit

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