Three-Dimensional Imaging and Roughness Characterization of Articular Cartilage by 50 Mhz Echography
Osteoarthritis (OA) is a slowly progressive pathology which affects all tissues of the joint in different ways. The cartilage degeneration is the main characteristic of the disease. In the pathogenic sequence it undergoes morphological, structural, biochemical and functional changes. The earliest alterations of the cartilage are thickness variation and surface roughening (fibrillation and ulceration) followed by fissuring leading to extensive thinning and loss of the tissue at an advanced stage of the disease.1 At present, the recognition of OA occurs when it is extensive and the characteristic advanced pathological features appear on current diagnostic imaging modalities: radiography, computed tomography, conventional echography (7.5 MHz) and magnetic resonance imaging. These techniques underestimate the cartilage alterations, they are not sensitive to its minor changes and neither permit accurate measure of its thickness.2
KeywordsArticular Cartilage Subchondral Bone Intra Articular Injection Cartilage Surface Control Cartilage
Unable to display preview. Download preview PDF.
- 1.Aubray JH Jr, Sokoloff L, Pathology of ostcoarihriiis. In: Arthritis and Allied Conditions. Eleventh edition. Edited by DJ McCarty. Philadelphia, Lea & Fcbiger, 1571(1989).Google Scholar
- 3.Saïc d, A., Chćr in, E., Gaucher, H., Laugicr, P., Netter, P., Berger, G., In vitro quantitative assessement of early and progressive lesions in a model of experimental ostcoarthritis by high resolution ultrasound, IEEE Ultrasonics Symposium, 95 CH35844, 1295(1995).Google Scholar
- 4.Saïc d, A., Chcrin, E., Gaucher, H., Laugicr, P., Gillct, P., Netter, P., Berger, G., In Vitro 50 MHz Echography of early and progressive articular cartilage and subchondral bone changes in a chemically indued ostcoarthritis (in press).Google Scholar