Optical Sensing of Red Blood Cell Dynamics

  • YongKeun Park
  • Catherine A. Best
  • Gabriel Popescu


Human red blood cell membrane (RBC) has remarkable deformability, which is crucial for its oxygen transportation in the blood circulatory system. This deformability of the RBC membrane can be altered by several patho-physiological conditions. Here we present recent development of optical imaging techniques to measure dynamic fluctuations in the RBC membrane, from which RBC membrane mechanical properties are probed non-invasively.


Optical Coherence Tomography Biconcave Shape Membrane Fluctuation Hereditary Elliptocytosis Reflection Interference Contrast Microscopy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors are grateful for the mentoring provided by the late Michael Feld. The authors acknowledge fruitful collaborations with the groups lead by Subra Suresh, Alex Levine, Nir Gov, and Sam Safran.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • YongKeun Park
  • Catherine A. Best
  • Gabriel Popescu
    • 1
  1. 1.Department of Electrical and Computer Engineering, Quantitative Light Imaging Laboratory, Beckman Institute for Advanced Science and TechnologyUniversity of Illinois at Urbana-ChampaignUrbanaUSA

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