Overview of Automated Immunohistochemistry

  • Jeffrey Prichard
  • Angela Bitting
  • Joe Myers


The past decade has produced major innovations and a great variety of features available in automated staining instruments. This chapter is a “buyer’s guide” for automated IHC instruments. For those new to the topic of automated staining, it begins with discussions of the advantages and disadvantages of automated versus manual staining techniques to help you decide if automation is the right choice for your laboratory. The basics of the general types of mechanics that differentiate the platforms are illustrated. Industry jargon about “open” and “closed” systems are better defined. To help with creating a thoughtful business plan to justify the budget expense of automation, the considerations that include the cost and potential savings of operating the equipment over and above the purchase price are presented. The different strategies for slide capacity and continuous processing that affect overall test throughput are described. A comprehensive feature comparison table is included to reveal how the current clinical instruments stack up side by side. With the information in this chapter you will know how to evaluate whether an instrument is right for you and understand the value of technological advancements as they arrive in the future.


Automation Instrument Cost Slide capacity Waste Predilute Barcode 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Jeffrey Prichard
    • 1
  • Angela Bitting
    • 1
  • Joe Myers
  1. 1.Department of Pathology and Laboratory MedicineGeisinger Medical CenterDanvilleUSA

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