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Adrenal Gland

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Handbook of Practical Immunohistochemistry

Abstract

This chapter is an overview of frequently used markers in the differential diagnosis of both common and rare tumors of the adrenal gland, with a focus on the effective markers employed for differentiating primary adrenal tumors and their mimics including metastatic renal cell carcinoma, hepatocellular carcinoma, and malignant melanoma. Other useful panels in the differential diagnosis of pheochromocytoma, adrenal cortical neoplasms, and small blue cell tumors are also addressed. There are 19 tables in this chapter with immunohistochemical markers answering questions that may arise when examining hematoxylin and eosin-stained tumor sections. A summary of useful and frequently used markers is also provided, in addition to some representative photomicrographs, and the author’s experience with a few tested antibodies. The effective diagnostic panels of antibodies for several entities are outlined.

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Authors and Affiliations

  1. Clinical Professor, Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA, USA

    Hanna G. Kaspar (Staff Pathologist)

  2. Geisinger Wyoming Valley Medical Center, 1000 East Mountain Blvd., Wilkes-Barre, PA, 18711, USA

    Hanna G. Kaspar (Staff Pathologist)

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  1. Hanna G. Kaspar
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  1. , Pathology and Laboratory Medicine, Geisinger Health System, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Fan Lin

  2. , Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Jeffrey Prichard

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Kaspar, H.G. (2011). Adrenal Gland. In: Lin, F., Prichard, J. (eds) Handbook of Practical Immunohistochemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8062-5_12

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