Echinoderm Immunity

  • L. Courtney Smith
  • Julie Ghosh
  • Katherine M. Buckley
  • Lori A. Clow
  • Nolwenn M. Dheilly
  • Tor Haug
  • John H. Henson
  • Chun Li
  • Cheng Man Lun
  • Audrey J. Majeske
  • Valeria Matranga
  • Sham V. Nair
  • Jonathan P. Rast
  • David A. Raftos
  • Mattias Roth
  • Sandro Sacchi
  • Catherine S. Schrankel
  • Klara Stensvåg
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 708)


A survey for immune genes in the genome for the purple sea urchin has shown that the immune system is complex and sophisticated. By inference, immune responses of all echinoderms may be similar. The immune system is mediated by several types of coelomocytes that are also useful as sensors of environmental stresses. There are a number of large gene families in the purple sea urchin genome that function in immunity and of which at least one appears to employ novel approaches for sequence diversification. Echinoderms have a simpler complement system, a large set of lectin genes and a number of antimicrobial peptides. Profiling the immune genes expressed by coelomocytes and the proteins in the coelomic fluid provide detailed information about immune functions in the sea urchin. The importance of echinoderms in maintaining marine ecosystem stability and the disastrous effects of their removal due to disease will require future collaborations between ecologists and immunologists working towards understanding and preserving marine habitats.


Antimicrobial Peptide Herule Cell Invertebr Pathol Discoidal Cell Cucumaria Frondosa 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • L. Courtney Smith
    • 1
  • Julie Ghosh
    • 1
  • Katherine M. Buckley
    • 2
  • Lori A. Clow
    • 3
  • Nolwenn M. Dheilly
    • 4
  • Tor Haug
    • 5
  • John H. Henson
    • 6
  • Chun Li
    • 5
  • Cheng Man Lun
    • 1
  • Audrey J. Majeske
    • 1
  • Valeria Matranga
    • 7
  • Sham V. Nair
    • 4
  • Jonathan P. Rast
    • 2
  • David A. Raftos
    • 4
  • Mattias Roth
    • 4
  • Sandro Sacchi
    • 1
  • Catherine S. Schrankel
    • 1
  • Klara Stensvåg
    • 5
  1. 1.Department of Biological SciencesGeorge Washington UniversityWashington DCUSA
  2. 2.Department of Medical Biophysics and Department of Immunology, Sunnybrook Health Sciences CentreUniversity of TorontoTorontoCanada
  3. 3.US Patent and Trademark OfficeAlexandriaUSA
  4. 4.Department of Biological SciencesMacquarie UniversitySydneyAustralia
  5. 5.Norwegian College of Fishery ScienceUniversity of TromsoTromsoNorway
  6. 6.Department of Biology and the Biochemistry and Molecular Biology ProgramDickinson CollegeCarlisleUSA
  7. 7.CNRInstitute of Biomedicine and Molecular Immunology “Albert Monroy”PalermoItaly

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