Abstract
Nowadays, a hot topic in the field of epilepsy research is the detection of any reliable marker, embedded in the electroencephalograms (EEGs), that can be exploited to predict the seizure with a sufficient advance notice. A useful analytical tool which may help epileptologists to unveil significant patterns in EEGs of people suffering from epilepsy is the Recurrence Quantification Analysis (RQA). This technique can be easily exploited by researchers since RQA software applications and related source codes are freely available. Nevertheless, the analysis of extensive EEGs can be considerably CPU-time-consuming so researchers are often obliged to strongly reduce the amount of data RQA is applied to. High throughput computing appears as the best solution to solve this problem. In this paper we present the preliminary results of the RQA performed on the EEGs of four epileptic patients who underwent pre-surgical evaluation for the resection of epileptic foci. In this study, EEGs were segmented in epochs of proper length each one analysed independently from the others using a Grid computing infrastructure.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Fisher R, van Emde Boas W, Blume W, Elger C, Genton P, Lee P, Engel J (2005). "Epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)". Epilepsia 46 (4): 470–472.
Rizzi M (2009) “During a systemic inflammatory response, the effect of non-steroidal anti-inflammatory drugs on seizure susceptibility in the immature brain may depend on the proconvulsant and anticonvulsant mechanisms simultaneously induced by the elevation of parenchymal prostaglandin E2 levels”. Biosci. Hypotheses 2 (3):143-147.
Sisodiya S (2003) “Drug resistance in epilepsy: not futile, but complex?”. Lancet Neurol 2(6):331.
Engel J Jr (1996). "Surgery for seizures". New Eng. J. Med. 334 (10): 647–652.
Paglioli E, Palmini A, Paglioli E, da Costa JC, Portuguez M, Martinez JV, Calcagnotto ME, Hoefel JR, Raupp S, Barbosa-Coutinho L (2004) “Survival analysis of the surgical outcome of temporal lobe epilepsy due to hippocampal sclerosis”. Epilepsia 45(11):1383-1391.
Webber CL Jr, Zbilut JP (1994) “Dynamical assessment of physiological systems and states using recurrence plot strategies”. J. Appl. Physiol 76:965-973.
Eckmann JP, Kamphorst SO, Ruelle D (1987) „Recurrence plots of dynamical systems”. Europhys. Lett. 5:973-977.
Marwan N, Romano RC, Thiel M, Kurths J (2007) “Recurrence plots for the analysis of complex systems”. Phys. Rep. 438:237-329.
Takens F (1981) “Detecting strange attractors in turbulence”. In: Rand DA, Young LS, editors. “Dynamical systems and turbulence”. Lecture Notes in Mathematics 898, Springer: 336.
Kantz H, Schreiber T (2004) “Nonlinear time-series analysis”. Cambridge.
Andronico, G. et al. (2003). GENIUS: a web portal for the grid. Nuclear Instruments and Methods in Physics Research, A 502, 433-436.
Barbera, R. et al. (2007). The GENIUS Grid Portal : Its Architecture, Improvements of Features, and New Implementations about Authentication and Authorization. Paper presented at the meeting Enabling Technologies: Infrastructure for Collaborative Enterprises. 16th IEEE International Workshops on. doi: 10.1109/WETICE.2007.4407171
Webber CL Jr (2005) “Recurrence Quantification Analysis of Nonlinear Dynamical Systems”. In Riley MA, Van Orden GC, editors. “Tutorials in contemporary nonlinear methods for the behavioural sciences”. 27-94.
Li X, Ouyang G, Yao X, Guan X (2004) “Dynamical characteristics of the pre-epileptic seizures in rats with recurrence quantification analysis”. Phys. Lett. A 333:164-171.
Theiler J, Eubank S, Longtin A, Galrikian B, Farmer J (1992) “Testing for nonlinearity in time series: the method of surrogate data”. Physica D 58:77-94.
Schreiber T, Schmitz A (2000) “Surrogate time series”. Physica D 142:346-382.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this paper
Cite this paper
Barbera, R., Rocca, G.L., Rizzi, M. (2011). Grid Computing Technology and the Recurrence Quantification Analysis to Predict Seizure Occurrence in Patients Affected by Drug-Resistant Epilepsy. In: Lin, S., Yen, E. (eds) Data Driven e-Science. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8014-4_37
Download citation
DOI: https://doi.org/10.1007/978-1-4419-8014-4_37
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-8013-7
Online ISBN: 978-1-4419-8014-4
eBook Packages: Computer ScienceComputer Science (R0)