Modeling Tumor Growth in Oncology

Chapter

Abstract

In cancer drug development, measurement of tumor growth is necessary for preclinical assessment of anticancer activity and clinical assessment of efficacy. This chapter reviews mathematical models of preclinical and clinical tumor growth. Issues and models with regards to mouse xenograft data will be highlighted.

Keywords

Placebo Toxicity Leukemia Shrinkage Paclitaxel 

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Copyright information

© American Association of Pharmaceutical Scientists 2011

Authors and Affiliations

  1. 1.Clinical Pharmacology, Modeling, and SimulationGlaxoSmithKlineDurhamUSA

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