We now know that almost every major biological process is controlled by protein assemblies composed of two or more proteins that interact with one another to exert their regulatory function . These assemblies are called protein machineries because the way that they work at a microscopic scale resembles the way that machines work at a macroscopic scale. Underlying these highly controlled activities are the ordered conformational changes that take place in the protein components of the machineries. These conformational changes often lead to molecular events that drive efficient regulation of the biological processes.
KeywordsHydrolysis Polypeptide Triphosphate Diphosphate Guanosine