Protein Sequencing

  • Engelbert Buxbaum


An important step in the characterisation of a new protein is the determination of its primary structure (amino acid sequence). This can be determined either by repeated chemical cleavage of terminal amino acids (either from the N- or C-terminal end, see Fig. 30.1 and Fig. 30.2 respectively), or by MS/MS.


Electron Capture Dissociation Electron Transfer Dissociation Cyanogen Bromide Collision Activate Dissociation Quadrupole Analyser 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.BiochemistryRoss University School of MedicineRoseauDominica

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