The Value of Vaccination

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 697)


Vaccination is most often studied from a scientific, clinical, or epidemiological perspective, and rightly so, for vaccines are meant to improve health outcomes. But these are not the only lenses through which the effects of vaccination programs can be understood. This chapter provides an economic perspective on vaccination programs, detailing in particular a new line of inquiry that makes a case for the importance of vaccination to achieving national economic aims. Research has shown that national spending on childhood vaccination programs does more than just reduce morbidity and mortality in a country: it also promotes national economic growth and poverty reduction. The chapter begins with a look at recent research that demonstrates powerful links that run from population health to economic well-being. Second, it discusses how knowledge of the economic benefits of health fundamentally transforms how we understand the value of vaccination. And third, it provides evidence for the scale of the returns that countries receive when they invest in immunization programs – returns that have not been fully captured by traditional economic analyses.


Vaccination Program Immunization Program Herd Immunity Childhood Vaccination Medical Care Cost 
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This chapter was presented at a course on “Hot Topics in Infection and Immunity in Children 2009” conducted at Oxford University, June 28–July 1, 2009. I am grateful to Jennifer O’Brien and also to Elizabeth Cafiero, Poting Cheung, Marija Ozolins, and Larry Rosenberg for the research and editorial assistance they provided in the preparation of this chapter.


  1. 1.
    United Nations. 2007. World Population Prospects 2006.Google Scholar
  2. 2.
    UNICEF. Young child survival and development [updated 2009; cited 2009 Oct 5]. Available from:
  3. 3.
    World Bank. 2008. World Development Indicators 2008, data for 2005.Google Scholar
  4. 4.
    Lim SS, Stein DB, Charrow A, Murray CJL. Tracking progress towards universal childhood immunisation and the impact of global initiatives: a systematic analysis of three-dose diphtheria, tetanus, and pertussis immunisation coverage. Lancet. 2008;372(9655):2031–46.CrossRefPubMedGoogle Scholar
  5. 5.
    Data source: United Nations [data on the Internet]. 2009. World Population Prospects 2008.Google Scholar
  6. 6.
    An early exposition of the arguments given here is Bloom DE, Canning D. The health and wealth of nations. Science. 2000;287:1207–9. A detailed account of the methodology and conclusions of some of this research appears in Bloom DE, Canning D. Global demographic change: dimensions and economic significance. Popul Dev Rev. 2008;34(S):17–51.Google Scholar
  7. 7.
    This relationship was originally highlighted in Preston S. The changing relation between mortality and level of economic development. Popul Stud. 1975;29(2): 231–48.Google Scholar
  8. 8.
    Data source: World Bank. 2008. World Development Indicators 2008.Google Scholar
  9. 9.
    These points are discussed in Bloom DE, Canning D, Jamison D. Health, wealth, and welfare. Finance Dev. 2004;41(1):10–15. (Translated into Spanish, French, Chinese, Russian, and Arabic. Reprinted in Giorgio S, editor. The Development Economics Reader. London: Routledge; 2008. p. 248–57.)Google Scholar
  10. 10.
    Alsan M, Bloom DE, Canning D. The effect of population health on foreign direct investment inflows to low- and middle-income countries. World Dev. 2006;34(4):613–30.CrossRefGoogle Scholar
  11. 11.
    Bloom DE, Canning D. The health and wealth of nations. Science. 2000;287:207–9.Google Scholar
  12. 12.
    Bärnighausen T, Bloom DE, Canning D, Friedman A, Levine O, O’Brien J, Privor-Dumm L, Walker D. The Economic Case for Expanding Vaccination Coverage of Children. Copenhagen Consensus Center Best Practice Paper Series, Copenhagen, Denmark: Copenhagen Consensus Center. Available from:
  13. 13.
    For an example of taking this broader view, see Bloom DE., Bärnighausen T, Canning D, O’Brien J. Accounting for the full benefits of childhood vaccination in South Africa. S Afr Med J. 2008;98(11):42–46.Google Scholar
  14. 14.
    Bloom DE, Canning D, Weston M. The value of vaccination. World Econ. July–Sep 2005;6(3):15–39. (Reprinted in Stevens P, editor. Fighting the diseases of poverty. London: International Policy Press; 2007. p. 214–38).Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Harvard School of Public HealthBostonUSA

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