Defining What Reproductive Laboratories Do



Reproductive laboratories should define the list of procedures under their scope of activity. Even though the embryology laboratory is the core of ART clinics, the roles of the andrology laboratory cannot be underestimated as it comes into play not only in the diagnosis of male factor infertility, which is contributory in 50–60 % of infertile couples, but also in infertility treatments. The typical clinical andrology laboratory performs some or all of the following diagnostic and therapeutic procedures: routine semen analysis, computer assisted semen analysis (CASA), semen biochemical tests, presence and quantification of seminal leukocytes, detection and quantification of antisperm antibodies in the semen, serum or cervical mucus, tests of sperm function (sperm membrane integrity, reactive oxygen species [ROS], seminal antioxidant capacity, sperm DNA integrity, acrosome reaction and sperm penetration assays), cryopreservation of spermatozoa (either ejaculated or surgically retrieved), and preparation of sperm for intrauterine insemination or in vitro fertilization.


Acrosome Reaction Infertile Couple Cervical Mucus Male Factor Infertility Intrauterine Insemination 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Esteves SC, Miyaoka R, Agarwal A. An update on the clinical assessment of the infertile male. Clinics (Sao Paulo). 2011;66(4):691–700.CrossRefGoogle Scholar
  2. 2.
    Cooper TG, Björndahl L, Vreeburg J, et al. Semen analysis and external quality control schemes for semen analysis need global standardization. Int J Androl. 2002;25:306–11.PubMedCrossRefGoogle Scholar
  3. 3.
    Alvarez C, Castilla JA, Ramírez JP, et al. External quality control program for semen analysis: Spanish experience. J Assist Reprod Genet. 2005;22:379–87.PubMedCrossRefGoogle Scholar
  4. 4.
    Keel B, Stembridge T, Pineda G, et al. Lack of standardization in performance of the semen analysis among laboratories in the United States. Fertil Steril. 2002;78:603–8.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.ANDROFERT, Andrology and Human Reproduction ClinicCampinasBrazil
  2. 2.Andrology Laboratory and Reproductive Tissue BankCenter for Reproductive Medicine, Cleveland Clinic FoundationClevelandUSA

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