The ART program in the National University Hospital (NUH) in Singapore started since the hospital opened in 1985. NUH is an acute care tertiary general hospital. Patients with infertility problems are either referred by family physicians or other gynecologists, or they may be self-referred. NUH is also a training hospital with a residency program in obstetrics and gynecology. Initially, the program was smaller, and the manpower via the nurses, laboratory personnel, embryologists, and physicians were fewer in numbers. When the numbers grew, it became evident that a quality management (QM) system was needed to standardize our functions and operations. If the growth of the ART program were to progress effectively, procedures need to be standardized. Any deficiency needed to be identified and dealt with early and efficiently.