• Alejandro Soto-Gutierrez
  • Nalu Navarro-Alvarez
  • Naoya Kobayashi
Part of the Molecular Pathology Library book series (MPLB, volume 5)


The ability of the liver to regenerate was recognized by the Greeks in the ancient myth of Prometheus, the Titan god of forethought, who gave fire to the mortals and angered Zeus. Zeus then punished him for his crime by having him bound to a rock while a great eagle ate his liver every day only to have it grow back to be eaten again the next day [1]. In contrast to other solid organs, the human liver has the unique ability to regenerate after toxic injury, chronic inflammation, and surgical resection and is able to restore its original mass, cellular structure and functions [1–3].


Primary Hepatocyte Constitutive Androstane Receptor Ethylene Glycol Tetraacetic Acid Ethylene Glycol Tetraacetic Acid Primary Human Hepatocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Alejandro Soto-Gutierrez
    • 1
  • Nalu Navarro-Alvarez
  • Naoya Kobayashi
  1. 1.Department of SurgeryUniversity of Pittsburgh School of Medicine/Children’s Hospital of Pittsburgh of UPMCPittsburghUSA

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