Development of the Inner Ear Efferent System
Roberts and Meredith (1992) wrote: “For more than forty years, the efferent supply to the mammalian ear provided by the olivocochlea bundle has been an enigma,” and this is still true today, in particular for the development of efferents. The inner ear efferents are so unique in their physiology, axonal course, and distribution that this adds to the mystery of their role in hearing and balance (Christopher Kirk and Smith 2003). However, analyzing the development of the vestibulocochlear efferent system may not only give us new insight into the development of this system but may also help to understand how the distribution and neurochemcial properties of the adult vestibulocochlear efferent system all come about.
KeywordsHair Cell Planar Cell Polarity Floor Plate Efferent Terminal Lateral Superior Olive
This work was supported by several NIH/NIDCD funds to some of the authors. We are indebted to the editors for help in stimulating this review.
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