Development of the Inner Ear Efferent System

  • Dwayne Simmons
  • Jeremy Duncan
  • Dominique Crapon de Caprona
  • Bernd Fritzsch
Part of the Springer Handbook of Auditory Research book series (SHAR, volume 38)


Roberts and Meredith (1992) wrote: “For more than forty years, the efferent supply to the mammalian ear provided by the olivocochlea bundle has been an enigma,” and this is still true today, in particular for the development of efferents. The inner ear efferents are so unique in their physiology, axonal course, and distribution that this adds to the mystery of their role in hearing and balance (Christopher Kirk and Smith 2003). However, analyzing the development of the vestibulocochlear efferent system may not only give us new insight into the development of this system but may also help to understand how the distribution and neurochemcial properties of the adult vestibulocochlear efferent system all come about.


Hair Cell Planar Cell Polarity Floor Plate Efferent Terminal Lateral Superior Olive 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported by several NIH/NIDCD funds to some of the authors. We are indebted to the editors for help in stimulating this review.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Dwayne Simmons
  • Jeremy Duncan
  • Dominique Crapon de Caprona
  • Bernd Fritzsch
    • 1
  1. 1.Department of BiologyUniversity of IowaIowa CityUSA

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