Corticofugal Modulation and Beyond for Auditory Signal Processing and Plasticity

  • Nobuo Suga
  • Weiqing Ji
  • Xiaofeng Ma
  • Jie Tang
  • Zhongju Xiao
  • Jun Yan
Part of the Springer Handbook of Auditory Research book series (SHAR, volume 38)


The auditory system consists of the ascending and descending (corticofugal) ­systems. The corticofugal system forms multiple feedback loops with the ascending system, so that the neural mechanisms for auditory signal processing cannot be fully understood without the exploration of the function of the corticofugal system. Corticofugal modulation (changes in response properties evoked by the corticofugal system) of subcortical neurons for auditory signal processing is one of the most important functions of the auditory cortex in the cerebrum.


Auditory Cortex Good Frequency Cochlear Microphonic Central Auditory System Collicular Neuron 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Our work has been supported by a research grant from the National Institute on Deafness and Other Communication Disorders (DC000175). Suga’s collaborators active in the field of auditory physiology are listed as coauthors of this article. In addition to them, Syed M. Chowdhury, Enquan Gao, Masashi Sakai, Wei Yan, Yongkui Zhang, and Yungfeng Zhang contributed to our research on corticofugal modulation. We thank Ms. Sally E. Miller for editing this article.


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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Nobuo Suga
    • 1
  • Weiqing Ji
  • Xiaofeng Ma
  • Jie Tang
  • Zhongju Xiao
  • Jun Yan
  1. 1.Department of BiologyWashington UniversitySt. LouisUSA

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