Automatic and Robust System for Correcting Microarray Images’ Rotations and Isolating Spots

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 696)


Microarray images contain a large volume of genetic data in the form of thousands of spots that need to be extracted and analyzed using digital image processing. Automatic extraction, gridding, is therefore necessary to save time, to remove user-dependent variations, and, hence, to obtain repeatable results. In this research paper, an algorithm that involves four steps is proposed to efficiently grid microarray images. A set of real and synthetic microarray images of different sizes and degrees of rotations is used to assess the proposed algorithm, and its efficiency is compared with the efficiencies of other methods from the literature.


Vertical Profile Template Match Spot Image Microarray Image Horizontal Profile 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Electrical Engineering DepartmentUniversity of North DakotaGrand ForksUSA

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