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Predicting Individual Affect of Health Interventions to Reduce HPV Prevalence

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Software Tools and Algorithms for Biological Systems

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 696))

Abstract

Recently, human papilloma virus (HPV) has been implicated to cause several throat and oral cancers and HPV is established to cause most cervical cancers. A human papilloma virus vaccine has been proven successful to reduce infection incidence in FDA clinical trials, and it is currently available in the USA. Current intervention policy targets adolescent females for vaccination; however, the expansion of suggested guidelines may extend to other age groups and males as well. This research takes a first step toward automatically predicting personal beliefs, regarding health intervention, on the spread of disease. Using linguistic or statistical approaches, sentiment analysis determines a text’s affective content. Self-reported HPV vaccination beliefs published in web and social media are analyzed for affect polarity and leveraged as knowledge inputs to epidemic models. With this in mind, we have developed a discrete-time model to facilitate predicting impact on the reduction of HPV prevalence due to arbitrary age- and gender-targeted vaccination schemes.

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Notes

  1. 1.

    Naive Bayes (5-gram character smoothing) and Language-Model-based (8-gram) classifiers where also evaluated; however, they achieved a maximum 69% accuracy with domain-specific training.

References

  1. Anderson, R., Garnett, G.: Mathematical models of the transmission and control of sexually transmitted diseases. Sexually Transmitted Diseases 27(10), 636–643 (2000)

    Article  PubMed  CAS  Google Scholar 

  2. Bagni, R., Berchi, R., Cariello, P.: A comparison of simulation models applied to epidemics. Journal of Artificial Societies and Social Simulation 5(3) (2002)

    Google Scholar 

  3. Boccara, N., Cheong, K.: Critical behavior of a probabilistic automata network sis model for the spread of an infectious disease in a population of moving individuals. Journal of Physics A : Mathematical and General 26(5), 3707–3717 (1993)

    Article  Google Scholar 

  4. Boccara, N., Cheong, K., Oram, M.: A probabilistic automata network epidemic model with births and deaths exhibiting cyclic behavior. Journal of Physics A : Mathematical and General 27, 1585–1597 (1994)

    Article  Google Scholar 

  5. Corley, C.D.: Mining social media and social network simulation to advance epidemiology. PhD Dissertation, University of North Texas (2009)

    Google Scholar 

  6. Douglas, K., Collins, J., Warren, C., Kann, L., Gold, R., Clayton, S., Ross, J., Kolbe, L.: Youth risk behavior surveillance: National college health risk behavior survey–united states, 1995. MMWR CDC Surveillance Summaries : Morbidity and Mortality Weekly Report. CDC Surveillance Summaries / Centers for Disease Control 46(6), 1–56 (1997)

    Google Scholar 

  7. Eaton, D.K., Kann, L., Kinchen, S., Shanklin, S., Ross, J., Hawkins, J., Harris, W.A., Lowry, R., McManus, T., Chyen, D., Lim, C., Brener, N.D., Wechsler, H., for Disease Control, C., (CDC), P.: Youth risk behavior surveillance–united states, 2007. MMWR Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries / CDC 57(4), 1–131 (2008)

    Google Scholar 

  8. Garnett, G.: The geographical and temporal evolution of sexually transmitted disease epidemics. Sexually Transmitted Infections 78(Suppl I) (2002)

    Google Scholar 

  9. Garnett, G., Anderson, R.: Contact tracing and the estimation of sexual mixing patterns: The epidemiology of gonococcal infections. Sexually Transmitted Diseases 20(4), 181–191 (1993)

    Article  PubMed  CAS  Google Scholar 

  10. Goldie, S., Grima, D., Kohli, M., Wright, T., Weinstein, M., Franco, E.: A comprehensive natural history model of hpv infection and cervical cancer to estimate the clinical impact of a prophylactic hpv-16/18 vaccine. International Journal of Cancer 106, 896–904 (2003)

    Article  CAS  Google Scholar 

  11. Goldie, S., Kohli, M., Grima, D.: Projected clinical benefits and cost-effectiveness of a humanpapillomavirus 16/18 vaccine. Journal of the National Cancer Institute 96(8), 604–615 (2004)

    Article  PubMed  Google Scholar 

  12. Hughes, J., Garnett, G., Koutsky, L.: The theoretical population-level impact of a phrophylactic human papilloma virus vaccine. Epidemiology 13(6), 631–639 (2002)

    Article  PubMed  Google Scholar 

  13. Kulasingam, S., Myers, E.: Potentital health and economic impact of adding a human papillomvirus vaccine to screening programs. Journal of the American Medical Association 290(6), 781–789 (2003)

    Article  PubMed  Google Scholar 

  14. Miller, P.: pyMPI–an introduction to parallel python using MPI. Livermore National Laboratories (2002). URL https://computing.llnl.gov/code/pdf/pyMPI.pdf

  15. Rossum, G.V., Drake, F.: Python language reference. Network Theory Ltd (2003). URL http://www.altaway.com/resources/python/reference.pdf

  16. Sanders, G., Taira, A.: Cost effectiveness of a potential vaccine for human papillomavirus. Emerging Infectious Diseases 9(1), 37–48 (2003)

    PubMed  Google Scholar 

  17. Stefano, D., Fukś, H., Lawniczak, A.: Object-oriented implementation of CA/LGCA modeling applied to the spread of epidemics. In: Proceedings of Canadian Conference on Electrical and Computer Engineering, vol. 1, pp. 26–31 (2000)

    Google Scholar 

  18. Turner, K., Garnett, G., Steme, J., Low, N.: Investigating ethnic inequalities in the incidence of sexually transmitted infections: Mathematical modelling study. Sexually Transmitted Infections 80, 379–385 (2004)

    Article  PubMed  CAS  Google Scholar 

  19. Zelkowitz, R.: Cancer. HPV casts a wider shadow. Science 323(5914), 580–1 (2009). DOI 10.1126/science.323.5914.580

    CAS  Google Scholar 

Download references

Acknowledgements

This work was partially supported by the Technosocial Predictive Analytics Initiative, part of the Laboratory Directed Research and Development Program at Pacific Northwest National Laboratory (PNNL). PNNL is operated by Battelle for DOE under contract DE-ACO5-76RLO 1830.

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Correspondence to Courtney D. Corley .

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Corley, C.D., Mihalcea, R., Mikler, A.R., Sanfilippo, A.P. (2011). Predicting Individual Affect of Health Interventions to Reduce HPV Prevalence. In: Arabnia, H., Tran, QN. (eds) Software Tools and Algorithms for Biological Systems. Advances in Experimental Medicine and Biology, vol 696. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7046-6_18

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