Physical Exercise, Sports, and Diabetes

Part of the Endocrine Updates book series (ENDO, volume 29)


Physical exercise is an appropriate and effective medicine to cure and prevent type 2 diabetes mellitus. It exerts positive effects mainly by increasing insulin sensitivity in the most important insulin-sensitive tissue: skeletal muscle. In muscle, exercise promotes insulin action, mitochondrial biogenesis and activity, and lipid and glucose oxidation. There is evidence in the literature about the efficacy of both aerobic and endurance training in ameliorating glucose control. The combination of both types of exercise has greater beneficial effects. Motivation of the great majority of subjects with type 2 diabetes to long-term practice of exercise is possible if it is conducted with simple and reproducible strategies of counseling.


Physical Activity Mitochondrial Biogenesis Oxidative Capacity Increase Insulin Sensitivity Muscle Oxidative Capacity 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Internal Medicine, C.U.R.I.A.MO (Centro Universitario Ricerca Interdipartimentale Attività Motoria)University of PerugiaPerugiaItaly

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