Benign and Malignant Neoplasms of the Exocrine Pancreas

Chapter

Abstract

Pancreatic neoplasms represent a major health-care problem for the aging population. The elderly are at risk for the entire spectrum of benign and malignant pancreatic tumors. Pancreatic adenocarcinoma is the most frequent and clinically significant of these tumors. It is the fourth leading cause of cancer death in the United States, and its incidence is associated with advancing age. The diagnosis and treatment of pancreatic cancer often represents a significant clinical challenge in the elderly, as there is a significant bias against aggressive surgical treatment in this population. In recent years, however, advances in diagnostic techniques, improved outcomes with regionalization of care, and a deeper understanding of prognostic factors have improved our ability to treat this challenging disease. In addition to pancreatic adenocarcinoma, the recognition and diagnosis of benign and premalignant pancreatic tumors has become more common in the elderly. These tumors require a thorough understanding of their clinical behavior as one weighs these risks with the risk of surgery in the elderly population. Fortunately, many of these tumors are amenable to less invasive therapeutic procedures with lessened perioperative morbidity and mortality.

Keywords

Adenocarcinoma Morphine Neuropathy Smoke Neutropenia 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of SurgeryIndiana University HospitalIndianapolisUSA

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