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Benign Diseases of Stomach and Duodenum

  • Daniel Borja-Cacho
  • Selwyn M. Vickers
Chapter

Abstract

The stomach comprises five anatomical regions: the cardia, fundus, body or corpus, antrum, and pylorus. The cardia is contiguous to the lower esophageal sphincter and is the transition between the esophagus and the stomach. The cardia is used to create a reference horizontal plane that delimits the second and third regions of the stomach, the fundus, and corpus, respectively. The fundus is located above this horizontal plane. The body is delimited proximally by the horizontal plane at the level of the cardia and distally by the incisura angularis. The incisura angularis is located at the abrupt right angle created by the lesser curvature in the distal portion of the stomach; it marks the transition between the body and the antrum. The pylorus delimits the transition between the stomach and duodenum; it controls gastric emptying [1].

Keywords

Gastric Emptying Duodenal Ulcer Gastric Ulcer Pylorus Infection Peptic Ulcer Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Soybel DI (2005) Anatomy and physiology of the stomach. Surg Clin North Am 85:875–894PubMedCrossRefGoogle Scholar
  2. 2.
    Russo MA, Redel CA (2006) Anatomy, histology, embryology, and developmental anomalies of the stomach and duodenum. In: Feldman M, Friedman LS, Brandt LJ (eds) Sleisenger & Fordtran’s gastrointestinal and liver disease, 8th edn. Saunders Elsevier, Philadelphia, PA, pp 981–998Google Scholar
  3. 3.
    Mulholland MW (2006) Gastric anatomy and physiology. In: Mullholand MW, Lillemoe KD, Doherty GM, Maier RV, Upchurch JR (eds) Greenfield’s surgery, 4th edn. Lippincott Williams & Wilkins, Philadelphia, pp 722–735Google Scholar
  4. 4.
    Wallace JL (2008) Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn’t the stomach digest itself? Physiol Rev 88:1547–1565PubMedCrossRefGoogle Scholar
  5. 5.
    Eswaran S, Roy MA (2005) Medical management of acid-peptic disorders of the stomach. Surg Clin North Am 85:895–906PubMedCrossRefGoogle Scholar
  6. 6.
    Kuo P, Rayner CK, Horowitz M (2007) Gastric emptying, diabetes, and aging. Clin Geriatr Med 23:785–808PubMedCrossRefGoogle Scholar
  7. 7.
    Newton JL (2005) Effect of age-related changes in gastric physiology on tolerability of medications for older people. Drugs Aging 22:655–661PubMedCrossRefGoogle Scholar
  8. 8.
    Morley JE (2007) The aging gut: physiology. Clin Geriatr Med 23:757–767PubMedCrossRefGoogle Scholar
  9. 9.
    Newton JL (2004) Changes in upper gastrointestinal physiology with age. Mech Ageing Dev 125:867–870PubMedCrossRefGoogle Scholar
  10. 10.
    Salles N (2007) Basic mechanisms of the aging gastrointestinal tract. Dig Dis 25:112–117PubMedCrossRefGoogle Scholar
  11. 11.
    van Leerdam ME (2008) Epidemiology of acute upper gastrointestinal bleeding. Best Pract Res Clin Gastroenterol 22:209–224PubMedCrossRefGoogle Scholar
  12. 12.
    Martinez JP, Mattu A (2006) Abdominal pain in the elderly. Emerg Med Clin North Am 24:371–388PubMedCrossRefGoogle Scholar
  13. 13.
    Theocharis GJ, Arvaniti V, Assimakopoulos SF et al (2008) Acute upper gastrointestinal bleeding in octogenarians: clinical outcome and factors related to mortality. World J Gastroenterol 14:4047–4453PubMedCrossRefGoogle Scholar
  14. 14.
    Gralnek IM, Barkun AN, Bardou M (2008) Management of acute bleeding from a peptic ulcer. N Engl J Med 359:928–937PubMedCrossRefGoogle Scholar
  15. 15.
    Martin RF (2005) Surgical management of ulcer disease. Surg Clin North Am 85:907–929PubMedCrossRefGoogle Scholar
  16. 16.
    Vilaichone RK, Mahachai V, Graham DY (2006) Helicobacter pylori diagnosis and management. Gastroenterol Clin North Am 35:229–247PubMedCrossRefGoogle Scholar
  17. 17.
    Chey WD, Wong BC (2007) American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol 102:1808–1825PubMedCrossRefGoogle Scholar
  18. 18.
    Lehours P, Yilmaz O (2007) Epidemiology of Helicobacter pylori infection. Helicobacter 12(Suppl 1):1–3PubMedCrossRefGoogle Scholar
  19. 19.
    Behrman SW (2005) Management of complicated peptic ulcer disease. Arch Surg 140:201–208PubMedCrossRefGoogle Scholar
  20. 20.
    Go MF (2006) Drug injury in the upper gastrointestinal tract: nonsteroidal anti-inflammatory drugs. Gastrointest Endosc Clin N Am 16:83–97PubMedCrossRefGoogle Scholar
  21. 21.
    Huang JQ, Sridhar S, Hunt RH (2002) Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis. Lancet 359:14–22PubMedCrossRefGoogle Scholar
  22. 22.
    Fendrich V, Langer P, Waldmann J et al (2007) Management of sporadic and multiple endocrine neoplasia type 1 gastrinomas. Br J Surg 94:1331–1341PubMedCrossRefGoogle Scholar
  23. 23.
    Ellison EC (2008) Zollinger-Ellison syndrome: a personal perspective. Am Surg 74:563–571PubMedGoogle Scholar
  24. 24.
    Egan BJ, Katicic M, O’Connor HJ et al (2007) Treatment of Helicobacter pylori. Helicobacter 12(Suppl 1):31–37PubMedCrossRefGoogle Scholar
  25. 25.
    Robson AJ, Richards JM, Ohly N et al (2008) The effect of surgical subspecialization on outcomes in peptic ulcer disease complicated by perforation and bleeding. World J Surg 32:1456–1461PubMedCrossRefGoogle Scholar
  26. 26.
    Kocer B, Surmeli S, Solak C et al (2007) Factors affecting mortality and morbidity in patients with peptic ulcer perforation. J Gastroenterol Hepatol 22:565–570PubMedCrossRefGoogle Scholar
  27. 27.
    Esrailian E, Gralnek IM (2005) Nonvariceal upper gastrointestinal bleeding: epidemiology and diagnosis. Gastroenterol Clin North Am 34:589–605PubMedCrossRefGoogle Scholar
  28. 28.
    Ramakrishnan K, Salinas RC (2007) Peptic ulcer disease. Am Fam Physician 76:1005–1012PubMedGoogle Scholar
  29. 29.
    Yuan Y, Padol IT, Hunt RH (2006) Peptic ulcer disease today. Nat Clin Pract Gastroenterol Hepatol 3:80–89PubMedCrossRefGoogle Scholar
  30. 30.
    Laine L, McQuaid KR (2009) Endoscopic therapy for bleeding ulcers: an evidence-based approach based on meta-analyses of randomized controlled trials. Clin Gastroenterol Hepatol 7:33–47PubMedCrossRefGoogle Scholar
  31. 31.
    Boparai V, Rajagopalan J, Triadafilopoulos G (2008) Guide to the use of proton pump inhibitors in adult patients. Drugs 68:925–947PubMedCrossRefGoogle Scholar
  32. 32.
    Jaspersen D, Koerner T, Schorr W et al (1995) Helicobacter pylori eradication reduces the rate of rebleeding in ulcer hemorrhage. Gastrointest Endosc 41:5–7PubMedCrossRefGoogle Scholar
  33. 33.
    Rokkas T, Karameris A, Mavrogeorgis A et al (1995) Eradication of Helicobacter pylori reduces the possibility of rebleeding in peptic ulcer disease. Gastrointest Endosc 41:1–4PubMedCrossRefGoogle Scholar
  34. 34.
    Brandimarte G, Tursi A, di Cesare L, Gasbarrini G (1999) Antimicrobial treatment for peptic stenosis: a prospective study. Eur J Gastroenterol Hepatol 11:731–734PubMedCrossRefGoogle Scholar
  35. 35.
    Yusuf TE, Brugge WR (2006) Endoscopic therapy of benign pyloric stenosis and gastric outlet obstruction. Curr Opin Gastroenterol 22:570–573PubMedCrossRefGoogle Scholar
  36. 36.
    Kozarek RA, Botoman VA, Patterson DJ (1990) Long-term follow-up in patients who have undergone balloon dilation for gastric outlet obstruction. Gastrointest Endosc 36:558–561PubMedCrossRefGoogle Scholar
  37. 37.
    Solt J, Bajor J, Szabo M, Horvath OP (2003) Long-term results of balloon catheter dilation for benign gastric outlet stenosis. Endoscopy 35:490–495PubMedCrossRefGoogle Scholar
  38. 38.
    McLoughlin MT, Byrne MF (2008) Endoscopic stenting: where are we now and where can we go? World J Gastroenterol 14:3798–3803PubMedCrossRefGoogle Scholar
  39. 39.
    Borch K, Skarsgard J, Franzen L et al (2003) Benign gastric polyps: morphological and functional origin. Dig Dis Sci 48:1292–1297PubMedCrossRefGoogle Scholar
  40. 40.
    Ljubicic N, Kujundzic M, Roic G et al (2002) Benign epithelial gastric polyps–frequency, location, and age and sex distribution. Coll Antropol 26:55–60PubMedGoogle Scholar
  41. 41.
    Morais DJ, Yamanaka A, Zeitune JM, Andreollo NA (2007) Gastric polyps: a retrospective analysis of 26,000 digestive endoscopies. Arq Gastroenterol 44:14–17PubMedCrossRefGoogle Scholar
  42. 42.
    Park do Y, Lauwers GY (2008) Gastric polyps: classification and management. Arch Pathol Lab Med 132:633–640PubMedGoogle Scholar
  43. 43.
    Jain R, Chetty R (2009) Gastric hyperplastic polyps: a review. Dig Dis Sci 54(9):1839–1846PubMedCrossRefGoogle Scholar
  44. 44.
    Linhares MM, Filho BH, Schraibman V et al (2006) Dieulafoy lesion: endoscopic and surgical management. Surg Laparosc Endosc Percutan Tech 16:1–3PubMedCrossRefGoogle Scholar
  45. 45.
    Pathan NF, El-Fanek H (2006) A 70-year-old man with episodes of upper gastrointestinal bleeding. Dieulafoy lesion/malformation. Arch Pathol Lab Med 130:e27–e29PubMedGoogle Scholar
  46. 46.
    Sone Y, Kumada T, Toyoda H et al (2005) Endoscopic management and follow up of Dieulafoy lesion in the upper gastrointestinal tract. Endoscopy 37:449–453PubMedCrossRefGoogle Scholar
  47. 47.
    Lacy BE, Weiser K (2005) Gastric motility, gastroparesis, and gastric stimulation. Surg Clin North Am 85:967–987PubMedCrossRefGoogle Scholar
  48. 48.
    Hasler WL (2007) Gastroparesis: symptoms, evaluation, and treatment. Gastroenterol Clin North Am 36:619–647PubMedCrossRefGoogle Scholar
  49. 49.
    Guo JP, Maurer AH, Fisher RS, Parkman HP (2001) Extending gastric emptying scintigraphy from two to four hours detects more patients with gastroparesis. Dig Dis Sci 46:24–29PubMedCrossRefGoogle Scholar
  50. 50.
    Waseem S, Moshiree B, Draganov PV (2009) Gastroparesis: current diagnostic challenges and management considerations. World J Gastroenterol 15:25–37PubMedCrossRefGoogle Scholar
  51. 51.
    Park MI, Camilleri M (2006) Gastroparesis: clinical update. Am J Gastroenterol 101:1129–1139PubMedCrossRefGoogle Scholar
  52. 52.
    Mason RJ, Lipham J, Eckerling G et al (2005) Gastric electrical stimulation: an alternative surgical therapy for patients with gastroparesis. Arch Surg 140:841–846PubMedCrossRefGoogle Scholar
  53. 53.
    Pedrazzani C, Marrelli D, Rampone B et al (2007) Postoperative complications and functional results after subtotal gastrectomy with Billroth II reconstruction for primary gastric cancer. Dig Dis Sci 52:1757–1763PubMedCrossRefGoogle Scholar
  54. 54.
    Ukleja A (2005) Dumping syndrome: pathophysiology and treatment. Nutr Clin Pract 20:517–525PubMedCrossRefGoogle Scholar
  55. 55.
    Eagon JC, Miedema BW, Kelly KA (1992) Postgastrectomy syndromes. Surg Clin North Am 72:445–465PubMedGoogle Scholar
  56. 56.
    Wise SW (2000) Case 24: afferent loop syndrome. Radiology 216:142–145PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of MinnesotaMinneapolisUSA

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