Parathyroid Disease in the Elderly

  • Leslie S. Wu
  • Sanziana A. Roman
  • Robert Udelsman
Chapter

Abstract

The primary function of the parathyroid glands is to maintain calcium homeostasis through the secretion of parathyroid hormone (PTH). This hormone is regulated by serum calcium through calcium-sensing receptors (CaSRs) on the parathyroid cell surface. In turn, most peripheral tissues, primarily kidney and bone, have PTH receptors which can affect varying functions. In the past, disturbances in this system were difficult to recognize until the development of clinically significant disease. With the development of better biochemical assays for serum PTH and calcium levels, subclinical derangements can be diagnosed before patients become symptomatic. The management of patients with the broad spectrum of metabolic calcium disturbances remains controversial.

Keywords

Fatigue Osteoporosis Adenoma Dehydration Glucocorticoid 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Leslie S. Wu
    • 1
  • Sanziana A. Roman
  • Robert Udelsman
  1. 1.Department of SurgeryMaine Medical CenterPortlandUSA

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