Overall Assessment of the Aspirate: Diagnostic Clues
The questions that the pathologist tries to sequentially answer when evaluating fine needle aspiration biopsies of lymph nodes are Is the aspirate adequate? Is the nodule clinically considered to be a lymph node really a lymph node? Is the lymphadenopathy caused by a benign or malignant process? If it is a benign process, is it infectious? Can the infectious agent be identified? If it is malignant, is it a metastasis or lymphoma? If it is a metastasis what is the type (carcinoma, melanoma, sarcoma)? Where did it most likely originate? If it is lymphoma, is it non-Hodgkin or Hodgkin lymphoma? If it is non-Hodgkin lymphoma, is it of B or T cell type? What is the subtype? Is it possible to grade it? If it is Hodgkin lymphoma, is it possible to determine the subtype?
KeywordsLymphoid Cell Hodgkin Lymphoma Anaplastic Large Cell Lymphoma Fine Needle Aspirate Crush Artifact
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