Overall Assessment of the Aspirate: Diagnostic Clues

Part of the Essentials in Cytopathology book series (EICP, volume 10)


The questions that the pathologist tries to sequentially answer when evaluating fine needle aspiration biopsies of lymph nodes are Is the aspirate adequate? Is the nodule clinically considered to be a lymph node really a lymph node? Is the lymphadenopathy caused by a benign or malignant process? If it is a benign process, is it infectious? Can the infectious agent be identified? If it is malignant, is it a metastasis or lymphoma? If it is a metastasis what is the type (carcinoma, melanoma, sarcoma)? Where did it most likely originate? If it is lymphoma, is it non-Hodgkin or Hodgkin lymphoma? If it is non-Hodgkin lymphoma, is it of B or T cell type? What is the subtype? Is it possible to grade it? If it is Hodgkin lymphoma, is it possible to determine the subtype?


Lymphoid Cell Hodgkin Lymphoma Anaplastic Large Cell Lymphoma Fine Needle Aspirate Crush Artifact 
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Suggested Reading

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Lab. Medicine & PathologyUniversity of MinnesotaMinneapolisUSA
  2. 2.Outpatient Pathology AssociatesSacramentoUSA

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