Diagnostic Criteria, Classification and Nomenclature for Bladder Pain Syndrome

  • Joop P. van de Merwe
  • Jørgen Nordling
  • Pierre Bouchelouche
  • Mauro Cervigni
  • Magnus Fall
  • Jean-Jacques Wyndaele


Because the term “interstitial cystitis” (IC) has different meanings in different centres and different parts of the world, the International Society for the Study of Bladder Pain Syndrome (ESSIC) has worked to create a consensus on definitions, diagnosis and classification in an attempt to overcome the lack of international agreement on various aspects of IC. ESSIC has discussed definitions, diagnostic criteria and disease classification in four meetings and extended email correspondence.

As the name IC has become misleading, it was agreed to name the disease bladder pain syndrome (BPS). This name is in line with recent nomenclature recommendations by the European Association of Urology and is based on the axial structure of the International Association for the Study of Pain classification. BPS would be diagnosed on the basis of chronic pelvic pain, pressure or discomfort perceived to be related to the urinary bladder accompanied by at least one other urinary symptom such as persistent urge to void or urinary frequency. Confusable diseases as the cause of the symptoms must be excluded. Classification of BPS types might be performed according to findings at cystoscopy with hydrodistention and morphologic findings in bladder biopsies. The presence of other organ symptoms as well as cognitive, behavioural, emotional and sexual symptoms should be addressed.


Pain Syndrome Interstitial Cystitis International Continence Society Chronic Pelvic Pain Syndrome Bladder Pain Syndrome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Joop P. van de Merwe
    • 1
  • Jørgen Nordling
    • 2
  • Pierre Bouchelouche
    • 3
  • Mauro Cervigni
    • 4
    • 5
  • Magnus Fall
    • 6
  • Jean-Jacques Wyndaele
    • 7
  1. 1.Departments of Immunology and Internal Medicine, Erasmus MCUniversity Medical Center RotterdamRotterdamThe Netherlands
  2. 2.Department of Urology, Herlev HospitalUniversity of CopenhagenBagsvaerdDenmark
  3. 3.Department of Clinical Biochemistry, Koege HospitalUniversity of CopenhagenCopenhagenDenmark
  4. 4.Department of UrogynecologyS. Carlo-IDIRomeItaly
  5. 5.Department Obstetrics and GynecologyCatholic UniversityRomeItaly
  6. 6.Department of Urology, Institute of Clinical SciencesSahlgrens Academy at University of GothenburgGöteborgSweden
  7. 7.Department of UrologyUniversity Hospital Antwerp and Antwerp UniversityEdegemBelgium

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