Intravesical Therapy

  • Mauro Cervigni
  • Arndt van Ophoven


Instillation therapy remains an important therapeutic approach to bladder pain syndrome (BPS) for ameliorating or delaying recurrence of symptoms. Instillations of drugs into the bladder create a high concentration of drugs locally at the disease site without increasing systemic levels, which can explain the low risk of systemic side effects.

A large body of evidence supports the notion that symptoms of BPS emanate from underlying inflammation in the bladder. The intravesical route offers reasonable adjunctive therapies for immediate symptom relief during symptom flare-up. Disadvantages include the need for intermittent catheterization, which can be painful in BPS patients, the cost, and the general risk of iatrogenic infection.


Hyaluronic Acid International Prostate Symptom Score Urothelial Cell Intravesical Instillation Bladder Pain Syndrome 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of UrogynecologyS. Carlo-IDI, Catholic UniversityRomeItaly
  2. 2.Department Obstetrics and GynecologyCatholic UniversityRomeItaly
  3. 3.Division of Neuro-Urology, Marienhospital HerneUniversity Hospital of BochumHerneGermany

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