Urine Biomarkers and Bladder Pain Syndrome

  • Pierre Bouchelouche
  • Kirsten Bouchelouche


There is currently no specific diagnostic test for bladder pain syndrome (BPS). Potential diagnostic biomarkers with varying sensitivity and specificity for BPS have been described in urine, serum, and bladder tissue. However, the specificity of these tests for BPS has been questioned. Ideally, biomarkers should enable a definitive diagnosis of BPS in the face of competing potential etiologies, provide information about treatment impact, and play a central role in the development of novel therapeutic agents.

The search for noninvasive techniques for diagnosis of BPS has led to the study of urine biomarkers.

This article describes the current state of the art with regard to urine biomarkers of BPS, and describes the areas that need continuing research.


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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Smooth Muscle Research Center, Department of Clinical Biochemistry, Koege HospitalUniversity of CopenhagenCopenhagenDenmark

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