Abstract
Infertile men with severe male-factor infertility have significantly more DNA damage than fertile men. Sperm DNA damage has been shown to affect ART outcomes. DNA damage is increasingly being evaluated as a test in establishing its utility in ART. Various assays have become more common than others. This chapter describes one of the more commonly used assays to measure sperm DNA damage by the terminal deoxynucleotidyltransferase dUTP nick end labeling or the TUNEL assay [1–5].
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© 2011 Springer Science+Business Media, LLC
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Sharma, R., Agarwal, A. (2011). Measurement of DNA Damage in Spermatozoa by TUNEL Assay. In: Zini, A., Agarwal, A. (eds) Sperm Chromatin. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6857-9_36
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DOI: https://doi.org/10.1007/978-1-4419-6857-9_36
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