Polycystic Ovary Syndrome

  • Jennifer Rosenblum


Polycystic ovary syndrome (PCOS) is a spectrum of disease that is characterized by menstrual irregularity due to ovulatory dysfunction and hyperandrogenism. Presenting signs and symptoms are heterogeneous and may vary over time. It is associated with an increased risk of obesity and the metabolic syndrome as well as infertility. The diagnosis of PCOS should be considered in any adolescent girl with hirsuitism, severe acne, menstrual irregularity, or obesity.


Polycystic Ovary Polycystic Ovary Syndrome Congenital Adrenal Hyperplasia Medroxyprogesterone Acetate Menstrual Irregularity 
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References and Additional Readings

  1. Ehrmann DA. Polycystic ovary syndrome. New Engl J Med 2005;352:1223–36.PubMedCrossRefGoogle Scholar
  2. Nestler JE. Metformin for the treatment of polycystic ovary syndrome. New Engl J Med 2008;358:47–54.PubMedCrossRefGoogle Scholar
  3. Rosenfield RL. Clinical features and diagnosis of polycystic ovary syndrome in adolescents. Available at:
  4. Rosenfield RL. Treatment of polycystic ovary syndrome in adolescents. Available at:

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Division of Adolescent and Young Adult MedicineMassGeneral Hospital for ChildrenBostonUSA

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