Estimating Phylogenies from Molecular Data



Phylogenetic estimation from aligned DNA, RNA or amino acid sequences has attracted more and more attention in recent years due to its importance in analysis of many fine-scale genetic data. Nowadays, its application fields range from medical research to drug discovery, to epidemiology, to systematics and population dynamics. Estimating phylogenies involves solving an optimization problem, called the phylogenetic estimation problem (PEP), whose versions depend on the criterion used to select a phylogeny among plausible alternatives. This chapter offers an overview of PEP and discuss the most important versions that occur in the literature.


Edge Weight Evolutionary Distance Internal Vertex Molecular Sequence Maximal Lyapunov Exponent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Daniele Catanzaro acknowledges support from the Belgian National Fund for Scientific Research (F.N.R.S.) of which he is “Chargé de Recherches.” Raffaele Pesenti and the anonymous reviewers for their valuable comments on previous versions of the manuscript. Finally, thanks to Prof. Mike Steel and Dr. Rosa Maria Lo Presti for helpful and exciting discussions.


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Authors and Affiliations

  1. 1.Service Graphes and Mathematical Optimization, Computer Science DepartmentUniversité Libre de Bruxelles (U.L.B.)BrusselsBelgium

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