Closed-loop Neural Recording Amplifier Design Techniques



As previously described, in order to accommodate weak neural signals, we need sufficient amplification and signal conditioning at the front-end of a neural-recording system. Specifically, the requirements on the front-end amplifier can be summarized as below:
  • Input-referred noise voltage < 10 μ V

  • Midband gain ≌ 40 dB

  • Input impedance ≥ a few MΩs at 1 kHz

  • Pass-band compatible with the desired signals (see Table 2.1).

  • AC-coupled input in order to block DC offsets.

  • Small silicon area and no off-chip components.

  • CMRR, PSRR ≥ 60 dB

  • Power dissipation ≪ 100 μ W/channel


Input Transistor Compensation Capacitor Capacitive Divider Cascode Transistor Tail Current Source 
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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Electrical Engineering and Computer ScienceUniversity of TennesseeKnoxvilleUSA
  2. 2.Department of Electrical EngineeringUniversity of WashingtonSeattleUSA

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