Patient-Specific Modeling of Structure and Function of Cardiac Cells

  • Frank B. Sachse


Cardiovascular diseases (CVDs) are the major cause of death in the developed world. Also, CVDs produce significant economic burden on society [37]. Development and implementation of approaches for prevention, diagnosis, and treatment of CVDs constitute large-scale and long-term efforts of healthcare systems, industry, and academia. Despite significant advances in technologies such as cardiac imaging and medical devices in the last decades, there are still major gaps in our basic knowledge of CVDs and their diagnosis and treatment, in particular, in individual patients.


Cardiac Cell Congenital Heart Defect Hypoplastic Left Heart Syndrome Rectifier Potassium Current Myosin Interaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work has been supported by National Heart, Lung, and Blood Institute grant R01 HL094464, the Richard A. and Nora Eccles Fund for Cardiovascular Research, and awards from the Nora Eccles Treadwell Foundation.


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Authors and Affiliations

  1. 1.Nora Eccles Harrison Cardiovascular Research and Training Institute, and Bioengineering DepartmentUniversity of UtahSalt Lake CityUSA

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