Disorders of the Spleen

  • Melissa E. Danko
  • Henry E. Rice


Knowledge of the unique splenic anatomy is essential to guide surgical therapy. The spleen develops within the dorsal mesogastrium during the fifth week of gestation and is located in the left upper quadrant of the abdomen. It abuts the diaphragm superiorly, posteriorly, and laterally. The visceral relationships of the spleen include the left kidney, splenic flexure of the colon, stomach, and tail of the pancreas. The splenic capsule is covered by parietal peritoneum, except at the splenic hilum, and the peritoneum forms its suspensory ligaments.


Sickle Cell Disease Immune Thrombocytopenic Purpura Laparoscopic Splenectomy Hereditary Spherocytosis Splenic Hilum 
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Suggested Reading

  1. American Academy of Pediatrics Committee on Infectious Diseases. Policy statement: recommendations for the prevention of pneumococcal infections, including the use of pneumococcal conjugate ­vaccine (Prevnar), pneumococcal polysaccharide vaccine, and antibiotic prophylaxis. Pediatrics. 2000;106:362–6.CrossRefGoogle Scholar
  2. Farah RA, Rogers ZR, Thompson WR, et al. Comparison of laparoscopic and open splenectomy in children with hematologic disorders. J Pediatr. 1997;131:41–6.CrossRefPubMedGoogle Scholar
  3. Price VE, Blanchette VS, Ford-Jones EL. The prevention and management of infections in children with asplenia or hyposplenia. Infect Dis Clin North Am. 2007;21:697–710.CrossRefPubMedGoogle Scholar
  4. Rescorla FJ, West KW, Engum SA, et al. Laparoscopic splenic procedures in children: experience in 231 children. Ann Surg. 2007;246:683–8.CrossRefPubMedGoogle Scholar
  5. Rice HE, Oldham KT, Hillery CA, Skinner MA, O’Hara SD, Ware RE. Clinical and hematological benefits of partial splenectomy for congenital hemolytic anemias in children. Ann Surg. 2003;237:281–8.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of SurgeryDuke University Medical CenterDurhamUSA

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