Crohn’s Disease



Crohn’s disease is one of the two commonly seen inflammatory bowel diseases. As opposed to ulcerative colitis, which only directly affects the colon and rectum, Crohn’s disease can affect any part of the intestinal tract. It can also involve the full thickness of the bowel wall, which accounts for many of the complications seen with the disease. Surgery is not curative but is reserved for the treatment of complications that are refractory to medical management. The etiology is unknown but it is increasingly clear that most patients have a genetic predisposition, though what purported environmental triggers are involved is less clear. Medical therapy has improved significantly, especially with the development of infliximab and adalimumab, but the prevalence of the disease is increasing, more patients are being identified at a younger age, and many still develop complications that require surgical intervention.


Ulcerative Colitis Subtotal Colectomy Fecal Diversion Complex Fistula Ileal Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Bousvaros A, Antonioli DA, Colletti RB, et al. Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn’s and Colitis Foundation of America. J Pediatr Gastroenterol Nutr. 2007;44(5):653–74.CrossRefPubMedGoogle Scholar
  2. Carvalho R, Hyams JS. Diagnosis and management of inflammatory bowel disease in children. Semin Pediatr Surg. 2007;16(3):164–71.CrossRefPubMedGoogle Scholar
  3. Strong SA. Perianal Crohn’s disease. Semin Pediatr Surg. 2007;16(3): 185–93.CrossRefPubMedGoogle Scholar
  4. Vogel J, da Luz Moreira A, Baker M, Hammel J, Einstein D, Stocchi L, et al. CT enterography for Crohn’s disease: accurate preoperative diagnostic imaging. Dis Colon Rectum. 2007;50(11):1761–9.CrossRefPubMedGoogle Scholar
  5. Von Allmen D. Surgical management of Crohn’s disease in children. Curr Treat Options Gastroenterol. 2005;8(5):405–10.CrossRefGoogle Scholar
  6. Von Allmen D, Markowitz JE, York A, Mamula P, Shepanski M, Baldassano R. Laparoscopic-assisted bowel resection offers advantages over open surgery for treatment of segmental Crohn’s disease in children. J Pediatr Surg. 2003;38(6):963–5.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of General SurgeryChildren’s Hospital of PhiladelphiaPhiladelphiaUSA

Personalised recommendations