Disorders of the Thyroid and Parathyroid

  • William T. Adamson


Both functional and neoplastic thyroid disorders frequently challenge the pediatric surgeon. Symptoms of hyperthyroidism are the most common abnormality. Surgical treatment is occasionally indicated in hyperthyroid autoimmune conditions such as Graves’ disease or Hashimoto’s thyroiditis. Thyroid cancer is rare, with an overall incidence of 1/2,500 children. Presentation with a nodule or mass in the anterior neck demands a workup for thyroid malignancy. Both differentiated and medullary thyroid carcinoma are best treated with total thyroidectomy and appropriate lymph node dissection. Identification of non-malignant conditions requiring surgery and prompt diagnosis and treatment of a thyroid carcinoma are crucial elements of successful surgical management.


Thyroid Cancer Thyroid Carcinoma Thyroid Stimulate Hormone Parathyroid Gland Recurrent Laryngeal Nerve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Dinauer CA, Breuer C, Rivkees SA. Differentiated thyroid cancer in children: diagnosis and management. Curr Opin Oncol. 2008;20:59–65.CrossRefPubMedGoogle Scholar
  2. Gingalewski CA, Newman KD. Seminars: controversies in the management of pediatric thyroid malignancy. J Surg Oncol. 2006;94:748–52.CrossRefPubMedGoogle Scholar
  3. Kollars J, Zarroug AE, van Heerden J, et al. Primary hyperparathyroidism in pediatric patients. Pediatrics. 2005;115:974–80.CrossRefPubMedGoogle Scholar
  4. Massimino M, Collini P, Fagundes Leite S, et al. Conservative surgical approach for thyroid and lymph-node involvement in papillary thyroid carcinoma of childhood and adolescence. Pediatr Blood Cancer. 2006;46:307–13.CrossRefPubMedGoogle Scholar
  5. Schlosser K, Schmitt CP, Bartholomaeus JE, et al. Parathyroidectomy for renal hyperparathyroidism in children and adults. World J Surg. 2008;32:801–6.CrossRefPubMedGoogle Scholar
  6. Skinner MA, Moley JA, Dilley WG, et al. Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A. N Engl J Med. 2005;353: 1105–13.CrossRefPubMedGoogle Scholar
  7. Skinner MA, Safford SD. Endocrine disorders and tumors. In: Ashcraft KW, Holcomb III GW, Murphy GW, editors. Pediatric surgery. 4th ed. Philadelphia: Elsevier Saunders; 2005. p. 1088–104.Google Scholar
  8. Sosa JA, Udelsman R. Total thyroidectomy for differentiated thyroid cancer. J Surg Oncol. 2006;94:701–7.CrossRefPubMedGoogle Scholar
  9. The Canadian Pediatric Thyroid Nodule Study Group. The Canadian Pediatric Thyroid Nodule Study: an evaluation of current management practices. J Pediatr Surg. 2008;43:826–30.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of North Carolina School of Medicine, North Carolina Children’s HospitalChapel HillUSA

Personalised recommendations