Epidemiology of Systemic Fungal Diseases: An Overview

  • Benjamin J. Park
  • Tom M. Chiller
  • Mary E. Brandt
  • David W. Warnock


The epidemiology of systemic fungal diseases has evolved rapidly over the past 2 decades. Advances in medical treatment have led to improved survival in the general population, but these advances have also led to larger numbers of individuals (including those who have indwelling catheters, who are in intensive care, who have received various immunosuppressive therapies, and who are undergoing organ or stem cell transplantation) being at risk for fungal infection. The global human immunodeficiency virus (HIV) pandemic has led to unprecedented numbers of opportunistic fungal infections, including candidiasis, cryptococcosis, histoplasmosis, and penicilliosis. While the numbers have dropped dramatically in developed nations [1–4], many countries in sub-Saharan Africa [5–7] and parts of Asia [8–10] remain highly affected by these and other fungal diseases. Migration patterns, land use, and climate factors are thought to have contributed to a marked increase in the incidence of coccidioidomycosis [11] in the endemic areas of the southwestern USA and in the emergence of Cryptococcus gattii infections [12, 13] in British Columbia, Canada, and the Pacific northwestern USA.


Invasive Fungal Infection Cryptococcal Meningitis Public Health Authority Sentinel Surveillance Cryptococcal Disease 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Benjamin J. Park
    • 1
  • Tom M. Chiller
  • Mary E. Brandt
  • David W. Warnock
  1. 1.Mycotic Diseases Branch and Division of Foodborne, Bacterial, and Mycotic DiseasesCenters for Disease Control and PreventionAtlantaUSA

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