Within a few decades, Candida species have progressed from infrequent pathogens that were largely considered nuisance contaminants to important and common human pathogens causing a wide spectrum of superficial and deep disease. Superficial infections are frequently community acquired and responsible for considerable morbidity. In contrast, deep seated, invasive, and systemic Candida infections are usually nosocomial in origin. The pathogenesis and risk factors for superficial and deep candidiasis, although overlapping, are markedly different; hence, superficial infection uncommonly results in systemic disease. Matching the increased incidence of Candida infections has been the availability in the last 2 decades of successive generations of antifungal agents.


Candida Species Antifungal Therapy Invasive Candidiasis Candida Infection Vulvovaginal Candidiasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Division of Infectious DiseasesWayne State University School of Medicine, Detroit Medical CenterDetroitUSA

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