Liquid-Core Beads and Their Applications in Food, Biotechnology, and Other Fields

  • Amos Nussinovitch


In 1971, Maddox’s patent on soft gelatin capsules was approved. In 1980, Lim and Sun published their hallmark study in which microencapsulated islets were used as a bioartificial pancreas. In that manuscript, alginate-polylysine liquid-core capsules were produced and described. In the food area, Sneath’s patent (1975) and later, our group, contributed to the manufacture and study of liquid-core hydrocolloid capsules. This chapter describes these liquid-core capsules, both natural and synthetic, and the procedures used to produce them. Methods for including oil within these capsules are also provided, along with an overview of their biotechnological and special food applications. Additional biotechnological applications of liquid-core capsules include growth of microorganisms and activity of enzymes within them, and food applications include the manufacture of unique specialty foods and fruit products, and the encapsulation of aroma and health compounds, among others. The chapter also describes agricultural and environmental uses of liquid-core capsules, and illustrates some special applications: aids to quitting smoking, in the beauty industry for removal of body hair, and in the paper industry.


Calcium Alginate Liquid Core Hydrogel Membrane Soft Gelatin Capsule Alginate Capsule 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Institute of Biochemistry, Food Science and Human Nutrition, The Robert H. Smith Faculty of Agriculture, Food and EnvironmentThe Hebrew University of JerusalemRehovotIsrael

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