Kernicterus pp 227-234 | Cite as

Neurobehavioral Teratology

  • David W. McCandless
Part of the Contemporary Clinical Neuroscience book series (CCNE)


A question frequently asked relates to whether neonatal unconjugatedhyperbilirubinemia might, at relatively low levels, have an adverse effect on mentalacuity and behavior.The concept is that even when indirect bilirubin levels are in the 12–18 mg/100 ml range, some small amount of free unbound bilirubin could gain access to thebrain, and have a deleterious effect.The issue of free unbound bilirubin entering cerebraltissue is discussed in the chapter in this volume entitled “Hyperbilirubinemia Revisited.”


Newborn Infant Littermate Control Unconjugated Bilirubin Loud Tone Unconjugated Hyperbilirubinemia 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Cell Biology & AnatomyRosalind Franklin University of Medicine & Science, Chicago Medical SchoolNorth ChicagoUSA

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