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Assessing Ventricular Function

  • Nicolaas Westerhof
  • Nikolaos Stergiopulos
  • Mark I. M. Noble
Chapter

Abstarct

In the intact organism the Ventricular Function Curve is usually presented as the relation between Stroke Volume (or Cardiac Output or stroke work)) and ventricular filling. If we make a graph between filling volume and Cardiac Output, we can derive the Ventricular Function Curve from the pressure-volume relation as follows. If the aortic pressure and thus ventricular pressure in systole is kept constant (Starling experiment), Cardiac Output is proportional to end-diastolic volume (Chap. 13).

Keywords

Cardiac Output Stroke Work Arterial Load Global Ventricular Function Preload Recruitable Stroke Work 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Glower DD, Spratt JA, Snow ND, Kabas JS, Davis JW, Olson CO, Tyson GS, Sabiston DC Jr, Rankin JS. Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. Circulation 1984;71:994–1009.CrossRefGoogle Scholar
  2. 2.
    Drake-Holland AJ, Mills CJ, Noble MIM, Pugh S. The response to changes in filling and ­contractility of various indices of human left ventricular mechanical performance. J Physiol (Lond) 1990;422:29–39.Google Scholar
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    Prinzen, FW, Peschar M. Relation between the pacing induced sequence of activation and left ventricular pump function in animals. J Pacing Clin Electrophysiol 2002;25:484–498.CrossRefGoogle Scholar
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    Van den Bos GC, Elzinga G, Westerhof N, Noble MIM. Problems in the use of indices of myocardial contractility. Cardiovasc Res 1973;7:834–848.CrossRefGoogle Scholar
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    Brooks CIO, White PA, Staples M, Oldershaw PJ, Redington AN, Collins PD, Noble MIM. Myocardial contractility is not constant during spontaneous atrial fibrillation in patients. Circulation 1998;98:1762–1768.CrossRefGoogle Scholar

Copyright information

© Springer US 2010

Authors and Affiliations

  • Nicolaas Westerhof
    • 1
  • Nikolaos Stergiopulos
    • 2
  • Mark I. M. Noble
    • 3
  1. 1.Departments of Physiology and Pulmonology ICaR-VUVU University Medical CenterAmsterdamthe Netherlands
  2. 2.Laboratory of Hemodynamics and Cardiovascular TechnologySwiss Federal Institute of TechnologyLausanneSwitzerland
  3. 3.Cardiovascular MedicineAberdeen UniversityAberdeenScotland

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