Phylogeny of Major Intrinsic Proteins

  • Jonas Å. H. Danielson
  • Urban Johanson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 679)


Major intrinsic proteins (MIPs) form a large superfamily of proteins that can be divided into different subfamilies and groups according to phylogenetic analyses. Plants encode more MIPs than other organisms and seven subfamilies have been defined, whereof the Nodulin26-like major intrinsic proteins (NIPs) have been shown to permeate metalloids. In this chapter we review the phylogeny of MIPs in general and especially of the plant MIPs. We also identify bacterial NIP-like MIPs and discuss the evolutionary implications of this finding regarding the origin and ancestral transport specificity of the NIPs.


Horizontal Gene Transfer Intrinsic Protein Major Intrinsic Protein Peribacteroid Membrane Membrane Channel Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2010

Authors and Affiliations

  1. 1.Department of Biochemistry, Molecular Protein Science Centre, Centre for Chemistry and Chemical EngineeringLund UniversityLundSweden

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