Human Oral Bacterial Biofilms: Composition, Dynamics, and Pathogenesis

  • Robert J. PalmerJr
  • Richard Darveau
  • Richard J. Lamont
  • Bente Nyvad
  • Ricardo P. Teles
Chapter

Abstract

The oral cavity has a diverse and dynamic bacterial flora that is significantly more complex than other sites in and on the human body, with the exception of the gut. Bacterial communities differ in composition depending on location in the mouth. Spatial relationships within the communities seem to be important for their function. Composition of the communities varies temporally and spatially: Changes in composition drive oral disease such as caries and periodontitis. Host response is key in the latter disease.

Keywords

Carbohydrate Fluoride Polysaccharide Pyruvate Fructose 

Notes

Acknowledgements

Robert J. Palmer Jr. is supported by the Intramural Research Program, National Institute of Dental and Craniofacial Research, National Institutes of Health.

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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Robert J. PalmerJr
    • 1
  • Richard Darveau
    • 2
  • Richard J. Lamont
    • 3
  • Bente Nyvad
    • 4
  • Ricardo P. Teles
    • 5
  1. 1.Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaUSA
  2. 2.Department of PeriodonticsUniversity of WashingtonSeattleUSA
  3. 3.Department of Oral BiologyUniversity of Florida College of DentistryGainesvilleUSA
  4. 4.School of Dentistry, Faculty of Health SciencesUniversity of AarhusAarhusDenmark
  5. 5.Department of PeriodontologyThe Forsyth InstituteBostonUSA

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