Systemic Treatment of Metastatic Breast Cancer

  • Leona Downey
  • Robert B. Livingston


Marked advancements are being made in the treatment of early-stage breast cancer, but many women still develop recurrence and metastasis. In addition, 5–10% of breast cancer patients have metastatic disease at presentation. While treatments for metastatic breast cancer continue to improve, there remains no cure once distant metastases develop, and over 40,000 women die of advanced disease annually in the United States alone. Balancing therapeutic efficacy in relation to side effects is critical. This chapter provides an overview of systemic therapy options for patients with metastatic breast cancer.


Breast Cancer Estrogen Receptor Metastatic Breast Cancer Vinca Alkaloid Initial Chemotherapy 
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Copyright information

© Springer New York 2010

Authors and Affiliations

  • Leona Downey
    • 1
  • Robert B. Livingston
    • 1
  1. 1.Arizona Cancer Center Clinical Research Shared Service, Arizona Cancer CenterUniversity of Arizona College of MedicineTucsonUSA

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