Controversial Indications for Breast Conserving Therapy and Radiation
Breast conserving surgery followed by radiation therapy is the accepted standard of care for a majority of women with early-stage invasive breast cancer and ductal carcinoma in situ. While there are relatively few contraindications to breast conserving surgery, there are several areas of controversy and special circumstances in the selection of patients for breast conserving therapy followed by radiation therapy to the whole breast that warrant specific discussion. Discussed in this chapter is breast conserving surgery in the setting of BRCA1/2 mutations, in the setting of collagen vascular disease, and in women who received prior radiation therapy to the chest for Hodgkin’s disease or other malignancies.
KeywordsBreast Cancer Contralateral Breast Contralateral Breast Cancer Local Relapse Breast Irradiation
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