Controversial Indications for Breast Conserving Therapy and Radiation



Breast conserving surgery followed by radiation therapy is the accepted standard of care for a majority of women with early-stage invasive breast cancer and ductal carcinoma in situ. While there are relatively few contraindications to breast conserving surgery, there are several areas of controversy and special circumstances in the selection of patients for breast conserving therapy followed by radiation therapy to the whole breast that warrant specific discussion. Discussed in this chapter is breast conserving surgery in the setting of BRCA1/2 mutations, in the setting of collagen vascular disease, and in women who received prior radiation therapy to the chest for Hodgkin’s disease or other malignancies.


Breast Cancer Contralateral Breast Contralateral Breast Cancer Local Relapse Breast Irradiation 


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Copyright information

© Springer New York 2010

Authors and Affiliations

  1. 1.Department of Radiation Oncology, Cancer Institute of New Jersey, Robert Wood Johnson Medical SchoolUniversity of Medicine and DentistryNew BrunswickUSA

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