Bone Marrow

  • Dennis P. O’Malley


The chapter examines pathologic findings seen in the human bone marrow. Diagnostic criteria are based on the 2008 WHO classification of hematologic neoplasms. Topics covered include myeloid neoplasms of the bone marrow, including both chronic and acute myeloid leukemias. Acute lymphoblastic leukemia is also covered. Diagnosis of myelodysplastic syndromes and the related myelodysplastic/myeloproliferative diseases are reviewed. Diagnosis of lymphoid disorders that involve the marrow are discussed. Anemias are covered. Finally, non-neoplastic lesions including infections, autoimmune manifestations, and other reactive conditions are covered.


Bone marrow Leukemia Lymphoma Infection Myeloproliferative neoplasms Myelodysplastic syndromes 



I would like to thank William G. Morice, M.D., Ph.D. for his chapter in the previous edition of this book that served as a model for the current version.


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Dennis P. O’Malley
    • 1
    • 2
  1. 1.Clarient Inc.Aliso ViejoUSA
  2. 2.Department of PathologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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